Antibody engineering is a sophisticated field within biotechnology that focuses on the design and modification of antibodies to enhance their therapeutic potential. By employing techniques such as recombinant DNA technology, scientists can create monoclonal antibodies with specific affinities and improved efficacy against target antigens. The engineering process often involves humanization, which reduces immunogenicity by modifying non-human antibodies to resemble human antibodies more closely. Additionally, methods like affinity maturation can be utilized to increase the binding strength of antibodies to their targets, making them more effective in clinical applications. Ultimately, antibody engineering plays a crucial role in the development of therapies for various diseases, including cancer, autoimmune disorders, and infectious diseases.
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