Synaptic plasticity rules are fundamental mechanisms that govern the strength and efficacy of synaptic connections between neurons in the brain. These rules, which include Hebbian learning, spike-timing-dependent plasticity (STDP), and homeostatic plasticity, describe how synapses are modified in response to activity. For instance, Hebbian learning states that "cells that fire together, wire together," implying that simultaneous activation of pre- and postsynaptic neurons strengthens the synaptic connection. In contrast, STDP emphasizes the timing of spikes; if a presynaptic neuron fires just before a postsynaptic neuron, the synapse is strengthened, whereas the reverse timing may lead to weakening. These plasticity rules are crucial for processes such as learning, memory, and adaptation, allowing neural networks to dynamically adjust based on experience and environmental changes.
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